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Accueil du site → Doctorat → Chine → 2020 → Genome-wide Characterization of the Sudanese and Chinese Indigenous Sheep Populations by High Density SNP Arrays

Chinese Academy of Agricultural Sciences (2020)

Genome-wide Characterization of the Sudanese and Chinese Indigenous Sheep Populations by High Density SNP Arrays

Adam Abied;

Titre : Genome-wide Characterization of the Sudanese and Chinese Indigenous Sheep Populations by High Density SNP Arrays

Auteur : Adam Abied;

Grade : Doctoral Dissertation 2020

Université : Chinese Academy of Agricultural Sciences

Résumé partiel
Through long term natural and artificial selection,domestic sheep(Ovis aries)have become adapted to a diverse range of ecological environments and display multiple phenotypic traits.Characterization of diversity and selection signature is essential for genetic improvement,understanding of environmental adaptation,as well as utilization and conservation of sheep genetic resources.The rapid development of high throughput genotyping such as high density SNP Bead Chip arrays and whole genome re-sequencing allow us to discover million SNPs of the individuals’ genome and quantify genome-wide genetic variation in sheep population.However,comprehensive researches are still limited and uncovered in Sudanese sheep as well as Chinses sheep to some extent.Here,we aimed to assess genetic diversity,population structure,and genomic selection among Sudanese native sheep and Chinese native sheep breeds using 600 K HD Bead Chip data.We collected a total of 280 individuals representing five Sudanese desert sheep AL-Ahamda(n =25),Buzee(n = 23),Hammri(n = 24),Kabashi(n =25)and Shanbali(n =24)with four Chinese sheep breeds Black Tibetan(n = 15),Oula(QOL =15),Tan(TS =18)and Zeku(n=15).Moreover,we compared five Chinese sheep breeds from extreme dry environments Hetian(n=19),Yabuyi(n= 20)and Karakul(n=20)and extreme humid environments Hu(n=17)and Wadi(n=17)sheep.In the second chapter,we provided a comprehensive literature review including the origin and domestication of sheep genetic resources in Africa and Asia,overview and distributions of Sudanese indigenous sheep,techniques and importance of molecular characterizations that make them importance targets for research,breeding and conservation.In third chapter,we investigated genome diversity,evolutionary relationship,population structure and genome-wide selection signatures between the five Sudanese thin-tailed desert sheep and four Chinese sheep breeds by using 600 K SNP Bead Chip in order to clearly characteristics the population and properly understand their genomics potential which provides a good opportunity for sustainable utilization,conservation and maintenance for genetic resources improvements in Sudanese sheep population

Mots clés : Sudan; China; adaptation; genetic diversity and selection sweep;

Présentation (CNKI)

Page publiée le 3 juin 2021