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Accueil du site → Projets de développement → Projets de recherche pour le Développement → 2021 → SPIDVAC Improved control of priority animal diseases : Novel vaccines and companion diagnostic tests for African horse sickness, peste des petits ruminants and foot-and-mouth disease

Commission Européenne (CORDIS) 2021

SPIDVAC Improved control of priority animal diseases : Novel vaccines and companion diagnostic tests for African horse sickness, peste des petits ruminants and foot-and-mouth disease

Animal Disease Vaccination Diagnostic

CORDIS (Service Communautaire d’Information sur la Recherche et le Développement) Commission Européenne

Titre : SPIDVAC Improved control of priority animal diseases : Novel vaccines and companion diagnostic tests for African horse sickness, peste des petits ruminants and foot-and-mouth disease

Code du projet : 101059924

Durée : Start date 1 July 2022 // End date 31 December 2025

Descriptif
Currently available vaccines for African horse sickness (AHS), peste des petits ruminants (PPR) and foot-and-mouth disease (FMD) demonstrate shortcomings, leaving the EU vulnerable to these transboundary farm animal diseases. The EU-funded SPIDVAC project is bringing together 13 international industry partners for the development of veterinary vaccines and diagnostic tools. The goal is to develop novel vaccines against AHS, PPR and FMD and, after evaluation in vitro, demonstrate their safety and efficacy in small-animal models and the target species. In addition, the consortium will develop a companion diagnostic test to identify infected and vaccinated animals. The project will increase understanding of infection mechanisms and evaluate the acceptability of vaccines for stakeholders in endemic areas.

Objectif
Current vaccines for African horse sickness (AHS), peste des petits ruminants (PPR) and foot-and-mouth disease (FMD) have critical shortcomings that leave the European Union vulnerable to these category A transboundary animal diseases, but control strategies that rely on culling alone are increasingly rejected by the public. At the same time, the risk of an introduction of AHS, PPR or FMD into Europe is growing, driven by climate change, global trade and long-distance travel. Innovative vaccines and companion diagnostics that are grounded in an increased knowledge of pathogenesis and immunity are urgently required to improve the capacity to prevent introductions and contain outbreaks, which are a major threat to European agriculture. The SPIDVAC (Safe Priority Infectious Diseases VACcines) consortium consists of 13 partners from Germany, France, Spain, the United Kingdom, the Netherlands, South Africa and Senegal, who will develop innovative vaccines against AHS, PPR and FMD and evaluate their capabilities in vitro, demonstrate the safety and efficacy of the candidate vaccines in small-animal models and in the target species and develop companion diagnostic to reliably differentiate between infected and vaccinated animals (DIVA). In addition, the project will increase knowledge on the mechanisms of infection, virulence and immunity and study the acceptability of vaccines for stakeholders in endemic areas. The consortium includes industry partners for veterinary vaccines and diagnostic tools, who will ensure the technological readiness and market relevance of the newly developed tools, which will help policy makers, veterinary services and business operators reduce the burden of infectious animal diseases, contribute to a sustainable livestock industry and promote public and animal health from farm to fork.

Participants au projet
Coordinateur : FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT

Budget
Coût total : € 1 388 037,50
Contribution UE : € 1 388 037,50

CORDIS

Page publiée le 21 novembre 2022