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University of South Australia (2016)

Discovery of antibacterial compounds from Australian eremophila plants

Biva, Israt Jahan

Titre : Discovery of antibacterial compounds from Australian eremophila plants

Auteur : Biva, Israt Jahan

Université de soutenance : University of South Australia

Grade : Doctor of Philosophy (PhD) 2016

Résumé
This thesis reports a study of the molecular structures and antibacterial activity of compounds extracted from Australian desert plants. With a rich diversity of chemical structures, phytochemicals can confer promising activity in preventing microbial infections through mechanisms that may differ from those of conventional antibiotics. Some plant-derived novel antibacterial compounds have shown inhibitory activity against a variety of human pathogens including multidrug-resistant bacteria. Plants of the endemic Australian genus Eremophila feature prominently in traditional Aboriginal medicinal lore and have shown great promise by providing some novel antibacterial compounds in previous studies. Therefore this thesis was designed to explore phytochemicals and their bioactivity from three unexplored species from this plant genus.

Mots clés : Eremophila (Plants) — Australia ; Phytochemicals ; Antibacterial agents

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Page publiée le 20 juillet 2017