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Texas Tech University (TTU) 2017

Biochemical studies in the elucidation of genes involved in tropane alkaloid production in Erythroxylum coca and Erythroxylum novogranatense

Estrada, Olga P.

Titre : Biochemical studies in the elucidation of genes involved in tropane alkaloid production in Erythroxylum coca and Erythroxylum novogranatense

Auteur : Estrada, Olga P.

Université de soutenance : Texas Tech University (TTU)

Grade : Master of Sciences (MS) 2017

Résumé
Natural products are vastly used in the modern pharmacopoeia. Among the most abundant natural products in medicine, there are tropane and granatane alkaloids. Efforts in the investigation of tropane and granatane biosynthesis are now contributing to the metabolic engineering sciences. Here, we present a portion of the most fundamental research in tropane alkaloid-producing transcriptomics with the use of qPCR techniques along with enzyme characterization experiments. In addition, a brief study on the enzyme responsible for the formation of methyl salicylate in Erythroxylum species is presented.

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Page publiée le 11 novembre 2018