Informations et ressources scientifiques
sur le développement des zones arides et semi-arides

Accueil du site → Doctorat → Israel → Reproduction and metabolism studies of xeric and mesic spiny mice (acomys) populations : comparative responses to photoperiod changes and hormonal treatments

Haïfa University (2013)

Reproduction and metabolism studies of xeric and mesic spiny mice (acomys) populations : comparative responses to photoperiod changes and hormonal treatments

Bukovetzky, Elena

Titre : Reproduction and metabolism studies of xeric and mesic spiny mice (acomys) populations : comparative responses to photoperiod changes and hormonal treatments

Auteur : Bukovetzky, Elena

Etablissement de soutenance : Haïfa University

Grade : Doctor of Philosophy (PhD) 2013

Résumé partiel
From an evolutionary point of view, reproduction timing is an important adaptation which enables the transfer of genetic properties, thus enabling species continuation. Rodents inhabiting arid environments need reliable cues for triggering their reproduction. A major gap in our knowledge exists with regards to : how reproduction is regulated by environmental signals in desert adapted rodents ? Results of previous studies have shown that activation of the reproductive system depends on photoperiod (as initial signal) and osmotic level changes (an ultimate regulator). Results of a comparative reproductive study revealed differences between desert-adapted Acomys russatus and Mediterranean (mesic) Acomys cahirinus populations with regards to environmental cues they rely on for activating their reproductive system. It was previously demonstrated that increased osmolarity levels (by gradually salinity treatment), or exogenous vasopressin (VP) treatment halts reproduction of desert adapted golden spiny mice A. russatus. For completing reproductive activity and feeding of the young, sufficient amounts of energy are requested. Therefore, food availability in the habitat or white adipose tissue (WAT) reserves are important for activating the reproductive system. For the last decades, WAT apart of its role in energy storage is also recognised as a multifunctional tissue ; in addition to the central role of lipid storage, it has a major endocrine function secreting several hormones, notably leptin. Leptin has been shown to promote sexual maturation in rodent species and a role in reproduction has been investigated at various sites within the hypothalamopituitary-gonadal axis. We aimed to determinate the pathways by which environmental changesaffect the reproductive system and metabolic status of desert-adapted common spiny mice, Acomys cahirinus, comparing with mesic A. cahirinus population. For this purpose, four studies were completed and results were published as three articles, and an additional manuscript was submitted.

Présentation

Page publiée le 26 novembre 2018